Neutrophils To Lymphocytes Ratio Formula:
From: | To: |
The Neutrophils To Lymphocytes Ratio (NLR) is a simple biomarker calculated from complete blood count (CBC) results. It represents the ratio of absolute neutrophil count to absolute lymphocyte count and is used as an indicator of systemic inflammation and immune response.
The calculator uses the NLR formula:
Where:
Explanation: The ratio provides insight into the balance between innate immunity (neutrophils) and adaptive immunity (lymphocytes) in the body.
Details: NLR has emerged as a valuable prognostic marker in various clinical conditions including infections, cardiovascular diseases, cancers, and inflammatory disorders. Elevated NLR values often indicate increased systemic inflammation.
Tips: Enter absolute neutrophil and lymphocyte counts from a complete blood count (CBC) test. Both values must be greater than zero for accurate calculation.
Q1: What is a normal NLR range?
A: Typically, a normal NLR ranges from 1-3, though this can vary slightly between laboratories and populations.
Q2: What does an elevated NLR indicate?
A: Elevated NLR (>3-5) may indicate increased systemic inflammation, infection, stress response, or could be associated with various pathological conditions.
Q3: Can NLR be used for cancer prognosis?
A: Yes, elevated NLR has been associated with poorer outcomes in various cancers and is used as a prognostic marker in oncology.
Q4: How often should NLR be monitored?
A: Monitoring frequency depends on the clinical context. For chronic conditions, it may be checked periodically, while in acute illnesses, more frequent monitoring may be necessary.
Q5: Are there limitations to NLR interpretation?
A: Yes, NLR should be interpreted in clinical context as various factors including medications, recent infections, and other conditions can affect the ratio.